The strongest oral medication blocks DHT to supercharge hair growth and maintain it.
Dutasteride is a medication that targets specific male hormones implicated in hair loss. It is typically prescribed in a 0.5 mg capsule for addressing male pattern baldness and other related conditions. Studies have shown that dutasteride halted further hair loss in 83% of men over a 2-year period, with 66% experiencing varying degrees of hair regrowth.
Dutasteride works by inhibiting both types of 5-alpha reductase enzymes (type 1 and type 2), which are responsible for converting testosterone into dihydrotestosterone (DHT). DHT is a potent male hormone implicated in male pattern baldness (androgenetic alopecia). By blocking these enzymes, dutasteride reduces the levels of DHT in the scalp, which helps to prevent hair follicle miniaturization and thereby slows down hair loss and promotes hair regrowth in some individuals.
Dutasteride, when taken orally in a 0.5 mg capsule, may lead to various side effects. Commonly reported side effects include sexual issues such as decreased libido, erectile dysfunction, and reduced ejaculate volume. Additionally, breast tenderness or enlargement (gynecomastia) can occur. Other common side effects may include impotence, testicular pain, dizziness, and weakness.
Less frequently, users may experience allergic reactions like rash or itching, as well as mood changes such as depression. Nausea and skin reactions are also possible but occur less commonly. In rare instances, serious side effects such as severe allergic reactions and prolonged, painful erections (priapism) have been reported.
Individual responses to dutasteride can vary, and not everyone will experience these effects. It’s crucial to discuss any concerns or potential side effects with a healthcare provider before starting dutasteride treatment.
Oral dutasteride is primarily used to treat benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges, causing difficulty urinating. It is also sometimes prescribed off-label for male pattern baldness (androgenetic alopecia).
Dutasteride works by inhibiting both types of 5-alpha reductase enzymes (type 1 and type 2), which are responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, dutasteride helps shrink the prostate gland in BPH and can also promote hair growth in male pattern baldness.
Common side effects of oral dutasteride include sexual side effects such as decreased libido, erectile dysfunction, and reduced ejaculate volume. Breast tenderness or enlargement (gynecomastia) may also occur. Less common side effects include impotence, testicular pain, dizziness, and weakness. Serious but rare side effects may include severe allergic reactions and prolonged, painful erections (priapism).
The effects of oral dutasteride on BPH symptoms can be noticeable within a few weeks to months of starting treatment. For male pattern baldness, it may take several months to see visible hair regrowth.
No, oral dutasteride should not be used by women, especially pregnant women or those planning pregnancy, due to the risk of harm to a developing male fetus. It is also not recommended for use in children. Dutasteride is specifically designed for use in adult men with conditions such as BPH or male pattern baldness.